Animal Care & Use

Regulatory Mandates

Regulatory Charges of the IACUC

  • Review the institution’s program for animal care and use at least biannually
  • Inspect all the institution’s animal facilities, including animal study areas and satellite facilities
  • Report to the Institutional Official on the above inspections and reviews and make recommendations for corrections
  • Investigate concerns involving the care and use of animals at the institution resulting from complaints from personnel at the institution or the public
  • Review proposed activities related to the care and use of animals including modifications to previously approved activities (protocol review).
  • Suspend an activity involving animals if it does not comply with PHS policy, AWRs, the Guide, or the University of Cincinnati’s Animal Welfare Assurance.

Committee Composition Requirements

  • The attending veterinarian who is certified by the American College of Laboratory Animal Medicine or has training or experience in laboratory animal science and medicine
  • An IACUC chair
  • At least one practicing scientist experience in research involving animals
  • At least one public member (nonaffiliated member) to represent the general community interests in the proper care and use of animals
  • At least one member whose primary concerns are in a nonscientific area (example: lawyer, ethicist, clergy)

The Public Health Service (PHS) through the Office of Laboratory Animal Welfare (OLAW) is charged with implementing the Health Research Extension Act (HREA) of 1985, as well as any policies/regulations established by PHS to implement HREA. The OLAW Tutorial on PHS Policy in an excellent source of knowledge for those wanting to learn more about the role the PHS plays in Laboratory Animal Welfare.


OLAW currently regulates all vertebrate species at institutions that receive federal funds.

Relevant Regulatory Documents

The United States Department of Agriculture (USDA) through the Animal and Plant Health Inspection Service (APHIS) is charged with implementing the Animal Welfare Act. The USDA has done so through the Animal Welfare Act Regulations and the Animal Care Policy Manual.


USDA-APHIS currently regulates any live or dead warm-blooded animal, which is being used for research, teaching, testing, experimentation, or exhibition purposes.

This term currently excludes: Birds, rats of the genus Rattus and mice of the genus Mus bred for use in research. Click here for more information on current efforts to efforts to coverage to include rats, mice, and birds. Farm animals used for improving animal nutrition, breeding, management, production efficiency, or for improving the quality of food or fiber are also excluded.

Relevant Regulatory Documents

The Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC) is a non-profit association that provides a voluntary accreditation program to institutions wishing to demonstrate the highest level of commitment to responsible care and use of animals.


AAALAC conducts site visits every three years to assess member institutions compliance with relevant animal care standards. AAALAC uses The Guide as its basis for accreditation. AAALAC's quarterly newsletter Connection is an excellent source of information for current issues facing the animal science community.


All vertebrate animals used or to be used in research, teaching or testing at accreditable units are to be included and evaluated in relation to the principles set forth in the Guide.

Relevant Regulatory Documents


Contact Us

The IACUC Office
University of Cincinnati
PO Box 210572
Cincinnati, OH 45221-0572
Phone: (513)558-5187
Fax: (513)558-3539